* For research use only, not for use in diagnostic procedures.
Zika fever (also known as Zika virus disease) is an illness caused by the Zika virus.
Most cases have no symptoms, but when present they are usually mild and can resemble dengue fever. Symptoms may include fever, red eyes, joint pain, headache, and a maculopapular rash. Symptoms generally last less than seven days. It has not caused any reported deaths during the initial infection. Infection during pregnancy causes microcephaly in some babies. Infections in adults has been linked to Guillain–Barré syndrome (GBS).
Zika fever is mainly spread via the bite of mosquitoes of the Aedes type. It can also be sexually transmitted from a man to his sex partners and potentially spread by blood transfusions. Infections in pregnant women can be spread to the baby.
The test is based on immunochromatography and can give a result within 15 minutes.
The Zika IgG/IgM Rapid Test is a qualitative membrane strip based immunoassay for the detection of Zika virus antibodies (IgG and IgM) in Whole Blood/Serum/Plasma. The test device consists of: 1) a burgundy colored conjugate pad containing Zika recombinant envelope antigens conjugated with Colloid gold (Zika conjugates), 2) a nitrocellulose membrane strip containing two test bands (T1 and T2 bands) and a control band (C band). The T1 band is pre-coated with the antibody for the detection of IgM anti- Zika, T2 band is coated with antibody for the detection of IgG anti- Zika. When an adequate volume of test specimen is dispensed into the sample well of the test cassette, the specimen migrates by capillary action across the cassette. IgG anti- Zika, if present in the specimen, will bind to the Zika conjugates. The immunocomplex is then captured by the reagent pre-coated on the T2 band, forming a burgundy colored T2 band, indicating a Zika IgG positive test result and suggesting a recent or repeat infection. IgM anti- Zika if present in the specimen will bind to the Zika conjugates. The immunocomplex is then captured by the reagent coated on the T1 band, forming a burgundy colored T1 band, indicating a Zika IgM positive test result and suggesting a fresh infection. Absence of any T bands (T1 and T2) suggests a negative result. To serve as a procedural control, a colored line will always appear at the control line region indicating that proper volume of specimen has been added and membrane wicking has occurred.