Fumonisin

Rapid CDIA^TM Fumonisin are intended for the qualitative detection of Fumonisin B1 in food.

Fumonisin B1 is the most prevalent member of a family of toxins, known as fumonisins, produced by several species of Fusarium molds, such as Fusarium verticillioides, which occur mainly in maize (corn), wheat and other cereals. Fumonisin B1 contamination of maize has been reported worldwide at mg/kg levels. Human exposure occurs at levels of micrograms to milligrams per day and is greatest in regions where maize products are the dietary staple.  It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase). Fumonisin B1 is hepatotoxic and nephrotoxic in all animal species tested. Their toxic effects in humans include neural tube defects, esophageal cancer, acute mycotoxicosis.