The CDIATM 6-Monoacetylmorphine Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of 6-Monoacetylmorphine and its metabolites in human urine.
6-MAM antigen is coated on the test region of the nitrocellulose membrane of the strips, and 6-MAM antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if 6-MAM in the sample is over the detection limit, line T is blank; on the other wise, if 6-MAM in the sample is less than the detection limit, line T is red.
6-Monoacetylmorphine (6-MAM) or 6-acetylmorphine (6-AM) is one of three active metabolites of heroin (diacetylmorphine), the others being morphine and the much less active 3-monoacetylmorphine (3-MAM). The production of black tar heroin results in significant amounts of 6-MAM in the final product. 6-MAM is approximately 30 percent more active than diacetylmorphine itself．This is why despite lower heroin content, black tar heroin may be more potent than some other forms of heroin. The CDIATM 6-Monoacetylmorphine Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of 6-Monoacetylmorphine in urine. The CDIATM 6-Monoacetylmorphine Colloidal Gold Test Cassette (Urine) yields a positive result when the 6-Monoacetylmorphine in urine exceeds 10 ng/mL.