CDIA™ Cotinine Colloidal Gold Test Cassette, Urine - Creative Diagnostics

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Drugs of Abuse Tests | Cotinine (COT) |

CDIATM Cotinine Colloidal Gold Test Cassette, Urine (DTS665)

Intended Use

The CDIATM Cotinine Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of cotinine and its metabolites in human urine.
  • Urine
  • Kit
  • 200 ng/mL

Principle Of The Test

Cotinine antigen is coated on the test region of the nitrocellulose membrane of the strips, and cotinine antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if cotinine in the sample is over the detection limit, line T is blank; on the other wise, if cotinine in the sample is less than the detection limit, line T is red.

General Description

Cotinine is the first-stage metabolite of nicotine, a toxic alkaloid that produces stimulation of the autonomic ganglia and central nervous system when in humans. Nicotine is a drug to which virtually every member of a tobacco-smoking society is exposed whether through direct contact or second-hand inhalation. In addition to tobacco, nicotine is also commercially available as the active ingredient in smoking replacement therapies such as nicotine gum, transdermal patches and nasal sprays. In a 24-hour urine, approximately 5% of a nicotine dose is excreted as unchanged drug with 10% as Cotinine and 35% as hydroxycotinine; the concentrations of other metabolites are believed to account for less than 5%. The CDIATM Cotinine Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of cotinine in urine. The CDIATM Cotinine Colloidal Gold Test Cassette (Urine) yields a positive result when the cotinine in urine exceeds 200 ng/mL.

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