The CDIATM Cu Colloidal Gold Test Cassette (Milk) is a lateral flow immunoassay for the detection of Cu in milk.
Cu antigen is coated on the test region of the nitrocellulose membrane of the strips, and Cu antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if Cu in the sample is over the detection limit, line T is blank; on the other wise, if Cu in the sample is less than the detection limit, line T is red.
Copper is a chemical element with symbol Cu (from Latin: cuprum). Copper in the blood and blood stream exists in two forms: bound to ceruloplasmin (85–95%), and the rest "free", loosely bound to albumin and small molecules. Free copper normally reduces oxidative stress, as it is involved in the metabolic elimination of reactive oxygen species, such as with the superoxide radical through Cu-Zn dependent superoxide dismutase. Excessive free copper impairs zinc homeostasis, and vice versa, which in turn impairs antioxidant enzyme function, increasing oxidative stress. Chronically elevated levels of copper intake produces zinc deficiency. The CDIATM Cu Colloidal Gold Test Cassette (Milk) is a lateral flow immunoassay for the detection of Cu in milk.