CDIA™ Cytomegalovirus (CMV) IgM/G Antibody Colloidal Gold Test Kit (serum/plasma/whole Blood) - Creative Diagnostics

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Infectious Disease Tests | Cytomegalovirus (CMV) |

CDIATM Cytomegalovirus (CMV) IgM/G Antibody Colloidal Gold Test Kit (serum/plasma/whole blood) (DTSJZ021)

Intended Use

The kit is used to detect the cytomegalovirus IgM/G antibody in serum/plasma/whole blood qualitatively. It is used as an aid in the diagnostic of past infection and epidemiological investigation.
  • Serum, Plasma, Whole blood
  • Kit

Principle Of The Test

The kit utilizes antibodies including a recombinant CMV antigen and goat anti-mouse IgG antibody on the nitrocellulose membrane with colloidal gold marked anti-human IgM/G as a mark tracer. The reagent is used to detect the CMV IgM/G according to the principle of capture method and gold immunochromatography assay. The sample mixing up anti-human IgM/G–marker move along the membrane to the T line, and form the T line with recombinant CMV antigen when the sample contains CMV IgM/G, which is a positive result. Conversely, it is a negative result.

General Description

Cytomegalovirus (CMV) is a herpes virus with the ability to remain dormant in the body for a long period of time. However, severe impairment of immune system by medication or disease can reactivate the virus from the latent or dormant state. CMV is a leading biological factor causing congenital abnormalities and complications among those who receive massive blood transfusions and immunosuppressive therapy. About half of pregnant women who contract a primary infection spread the disease to their fetus. In-utero infection may cause major defects including mental retardation, blindness, and/or deafness. Serological tests for detecting the presence of antibody to CMV can provide valuable information regarding the history of previous infection, diagnosis of active or recent infection, as well as in screening blood for transfusions in newborns and immunocompromised recipients. Antibody of the IgM class is produced during the first 2-3 weeks of infection with CMV and exists only transiently in most patients. Serologic procedures which measure the presence of IgM and IgG antibodies help discriminate between primary and recurrent infections since IgM antibodies are rarely found in recurrent infections.

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