CDIA™ Hepatitis B E Antibody Test Strip - Creative Diagnostics

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Infectious Disease Tests | Hepatitis B Virus |

CDIATM Hepatitis B e Antibody Test Strip (DTS363)

Intended Use

OneStep Anti-HBe Rapid Test is a colloidal gold enhanced immunoassay for the determination of antibodies to Hepatitis B e antigen (Anti-HBe) in human serum/plasma. The nitrocellulose membrane is immobilized with mouse Anti-HBeAg Mc-Ab on the test region. During the assay, the mixture of HBeAg and specimen is allowed to react with the colored conjugate (antibody-colloidal gold conjugate). The mixture then migrates on the membrane through capillary action.
  • Serum
  • Strip
  • 2.5ng/ml

Product Introduction

General Description
Hepatitis B is an infectious inflammatory illness of the liver caused by the hepatitis B virus (HBV) that affects hominoidea, including humans. About a third of the world population has been infected at one point in their lives, including 350 million who are chronic carriers. HBeAg is produced by proteolytic processing of the pre-core protein. Shortly after the appearance of the HBsAg, another antigen called hepatitis B e antigen (HBeAg) will appear. Traditionally, the presence of HBeAg in a host's serum is associated with much higher rates of viral replication and enhanced infectivity; however, variants of the hepatitis B virus do not produce the 'e' antigen, so this rule does not always hold true. During the natural course of an infection, the HBeAg may be cleared, and antibodies to the 'e' antigen (anti-HBe) will arise immediately afterwards. This conversion is usually associated with
a dramatic decline in viral replication.

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