CDIA^TM Human dengue virus IgG-IgM Test Kit (DTS350)

* For research use only, not for use in diagnostic procedures.

Intended Use

The Dengue IgG/IgM Rapid Test is a lateral flow immunoassay for the simultaneous detection and differentiation of IgG anti-dengue virus and IgM anti-dengue virus in human whole blood, serum or plasma. It is intended to be used by the professionals as a screening test and as an aid in the diagnosis of infection with dengue viruses.

Sample : Serum, plasma or whole blood
Test Format : Card
Sensitivity : 96.9%
Specificity : 98.9%

Product Introduction

General Description

Dengue viruses, a family of four distinct serotypes of viruses (Den 1,2,3,4), are single-strained, enveloped, positive-sense RNA viruses. The viruses are transmitted by mosquitoes of the daytime-biting Stegemyia family, principally Aedes aegypti, and Aedes albopictus. Today, more than 2.5 billion people living in the areas of tropical Asia, Africa, Australia, and the Americas are at risk for dengue infection. An estimated 100 million cases of dengue fever and 250,000 cases of life-threatening dengue hemorrhagic fever occur annually on a worldwide basis.Serological detection is a common method for the diagnosis of infection with dengue viruses. IgM anti-dengue virus starts to appear at 3 days after initial exposure and remain in the circulation for about 30-60 days. IgG anti-dengue virus raise at around 7 days, peak at 2-3 weeks, and persist for the life. The Dengue IgG/IgM Rapid Test detects IgG and IgM anti-dengue virus in one test within 25 minutes. The test is user friendly, without cumbersome laboratory equipment, and requires minimal staff trainings.

Principle Of The Test

The Dengue IgG/IgM Rapid Test Device (Whole Blood/Serum/Plasma) is a qualitative membrane-based immunoassay for the detection of Dengue antibodies in whole blood, serum, or plasma. This test consists of two components, an IgG component and an IgM component. In the IgG component, anti-human IgG is coated in test line region 1 of the test. During testing, the specimen reacts with Dengue antigen-coated particles in the test strip. The mixture then migrates upward on the membrane chromatographically by capillary action and reacts with the anti-human IgG in test line region 1. If the specimen contains IgG antibodies to Dengue, a colored line will appear in test line region 1. In the IgM component, anti-ligand is coated in test line region 2 of the test. During testing, the specimen reacts with ligand anti-human IgM. Dengue IgM antibodies, if present in the specimen, reacts with the ligand anti-human IgM and the Dengue antigen-coated particles in the test strip, and this complex is captured by the anti-ligand, forming a colored line in test line region 2. Therefore, if the specimen contains Dengue IgG antibodies, a colored line will appear in test line region 1. If the specimen contains Dengue IgM antibodies, a colored line will appear in test line region 2. If the specimen does not contain Dengue antibodies, no colored line will appear in either of the test line regions, indicating a negative result. To serve as a procedural control, a colored line will always appeared in the control line region, indicating that the proper volume of specimen has been added and membrane wicking has occurred.

Alternative Names: dengue rapid test kit, Dengue Fever IgG-IgM, Dengue IgG-IgM, Dengue Virus IgG-IgM

CDIA^TM Human Dengue Non-Structural Protein 1 Test Strip (DTS349)

Target: Human dengue Non-Structural Protein 1
Method: Colloidal Gold
Sample: Serum
Size: 25T

CDIA^TM Dengue IgG/IgM Rapid Test (DTSXYL1)

Target: Dengue IgG/ IgM and virus antigen (Dengue Ag)
Method: Colloidal Gold
Sample: Whole blood, serum, plasma
Size: 1T

CDIA^TM Dengue IgG/IgM/NS1 Combo Rapid Test (DTSXYL2)

Target: Dengue IgG/ IgM and virus antigen (Dengue Ag)
Method: Colloidal Gold
Sample: Whole blood, serum, plasma
Size: 1T

CDIATM Human dengue virus IgG-IgM Test Kit (DTS350)

CDIATM Human Dengue Non-Structural Protein 1 Test Strip (DTS349)

CDIATM Dengue IgG/IgM Rapid Test (DTSXYL1)

CDIATM Dengue IgG/IgM/NS1 Combo Rapid Test (DTSXYL2)

CDIA^TM Human dengue virus IgG-IgM Test Kit (DTS350)

CDIA^TM Human Dengue Non-Structural Protein 1 Test Strip (DTS349)

CDIA^TM Dengue IgG/IgM Rapid Test (DTSXYL1)

CDIA^TM Dengue IgG/IgM/NS1 Combo Rapid Test (DTSXYL2)