CDIA™ Human FOB+Tf (transferrin) Rapid Test - Creative Diagnostics

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Tumor/Cancer Markers Tests | Tf (transferrin) |

CDIATM Human FOB+Tf (transferrin) Rapid test (DTSXYZ7)

Intended Use

The FOB+Tf ( transferrin ) Rapid test is a rapid chromatographic immunoassay (non-invasive assay) for the qualitative detection of human haemoglobin (hHb) and human transferrin (hTf) in human feces specimens which might be useful for the diagnosis of bleeding gastrointestinal disorders.
  • Stool
  • Kit

Product Introduction

General Description

Colorectal cancer is cancer that occurs in the colon or rectum, and affects both men and women of all racial and ethnic groups, and is most often found in people aged 50 years or older. Fecal occult blood should be an important indicator in the diagnostic evaluation of patients with suspected gastrointestinal bleeding of any etiology, not just as an indication of colorectal cancer. The presence of human haemoglobin in feces is inadequate as a screening test for stomach cancer (upper gastrointestinal disorders), because of human haemoglobin derived from the upper digestive tract is broken down in the intestinal tract (the antigenicity is lost). Detection of fecal transferrin, which is more stable in stool than haemoglobin, provides an alternative way of diagnosing the disease in the upper digestive tract. 

Principle

The FOB+Tf ( transferrin ) Rapid test is a qualitative lateral flow immunoassay for the detection of human haemoglobin and human transferrin in human feces samples. The membrane is pre-coated with monoclonal antibodies against human haemoglobin and human transferrin on the test line region. During testing, the sample reacts with the particles coated with antihuman haemoglobin antibodies and/or with anti-human transferrin antibodies which were pre-dried on the test strip. The mixture moves upward on the membrane by capillary action. In the case of a positive result the specific antibodies present on the membrane will react with the mixture conjugates and generate one or two coloured lines. A green coloured line always appears in the control line and serves as verification that sufficient volume was added, that proper flow was obtained and as an internal control for the reagents.



                           Figure 1. Assay procedure (collected stool samples)

 


                                             Figure 2. Interpretation of results


Reagents And Materials Provided

1. Card tests 

2. Instructions for use 

3. Specimen collection vial with buffer

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