HIV Rapid Test (Serum) (Cassette) direct binding screening test for the presence of antibodies to HIV1 and HIV2 viruses.
Human immunodeficiency virus (HIV) is a lentivirus (a member of the retrovirus family) that causes acquired immunodeficiency syndrome (AIDS),a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive.
HIV infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages, and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: First, direct viral killing of infected cells; second, increased rates of apoptosis in infected cells; and third, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections.
Principle Of The Test
The test is based on the principle of double sandwich immunoassay for the determination of anti-HIV-1 and anti-HIV-2 in serum/plasma. Recombinant HIV antigens are employed to specifically identify anti-HIV antibodies specifically.This one step test is very sensitive and rapid.Test results are read visually without any instrumentation.