CDIA™ Marijuana Colloidal Gold Test Cassette, Saliva - Creative Diagnostics

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Drugs of Abuse Tests | Marijuana (THC) |

CDIATM Marijuana Colloidal Gold Test Cassette, Saliva (DTSJZ023)

Intended Use

The CDIATM Marijuana Colloidal Gold Test Cassette (Saliva) is an immunochromatography based one step in vitro test. It is designed for qualitative determination of marijuana metabolites (THC) in human oral fluid specimens. This assay provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/ mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the Substance Abuse Mental Health Services Administration (SAMHSA). Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated.
  • Saliva
  • Kit

Principle Of The Test

CDIATM Marijuana Colloidal Gold Test Cassette (Saliva) is an immunoassay based on the principle of competitive binding.
Drugs that may be present in the oral fluid specimen compete against their respective drug conjugate for binding sites on their specific antibody. During testing, a portion of the oral fluid specimen migrates upward by capillary action. A drug, if present in the oral fluid specimen below its cut-off concentration, will not saturate the binding sites of its specific antibody. The antibody will then react with the drug-protein conjugate and a visible colored line will show up in the test line region of the specific drug strip. The presence of drug above the cut-off concentration in the oral fluid specimen will saturate all the binding sites of the antibody. Therefore, the colored line will not form in the test line region. A drug-positive oral fluid specimen will not generate a colored line in the specific test line region of the stripbecause of drug competition, while a drug-negative oral fluid specimen will generate a line in the test line region because of the absence of drug competition. To serve as a procedural control, a colored line will always appear at the control line region, indicating that proper volume of specimen.

General Description

Tetrahydrocannabinol, the active ingredient in the marijuana plant (cannabis sativa), is detectable in saliva shortly after use. The detection of the drug is thought to be primarily due to the direct exposure of the drug to the mouth (oral and smoking administrations) and the subsequent sequestering of the drug in the buccal cavity. Historical studies have shown a window of detection for THC in saliva of up to 14 hours after drug use. The CDIATM Marijuana Colloidal Gold Test Cassette (Saliva) yields a positive result when the THC-COOH concentration exceeds 12 ng/mL.

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