The CDIATM Methamphetamine Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of methamphetamine and its metabolites in human urine.
Methamphetamine antigen is coated on the test region of the nitrocellulose membrane of the strips, and methamphetamine antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if methamphetamine in the sample is over the detection limit, line T is blank; on the other wise, if methamphetamine in the sample is less than the detection limit, line T is red.
Methamphetamine is an addictive stimulant drug that strongly activates certain systems in the brain. Methamphetamine is closely related chemically to amphetamine, but the central nervous system effects of methamphetamine are greater. Methamphetamine can be taken orally, injected, or inhale. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Methamphetamine is excreted in the urine as amphetamine and oxidized and deaminated derivatives. However, 10 to 20 % of Methamphetamine is excreted unchanged. Thus, the presence of the parent compound in the urine indicates Methamphetamine use. The CDIATM Methamphetamine Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of methamphetamine in urine. The CDIATM Methamphetamine Colloidal Gold Test Cassette (Urine) yields a positive result when the methamphetamine in urine exceeds 2000/1000/500/300 ng/mL.