The CDIATM Opiate Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of opiate and its metabolites in human urine.
Opiate antigen is coated on the test region of the nitrocellulose membrane of the strips, and opiate antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if opiate in the sample is over the detection limit, line T is blank; on the other wise, if opiate in the sample is less than the detection limit, line T is red.
Opiates refer to any drug that is derived from the opium poppy, including the natural products, morphine and codeine, and the semi-synthetic drugs such as heroin. Opiates exert their effects on the central nervous system and organs containing smooth muscle. Opiates manifest their presence by analgesia, drowsiness, euphoria, lowering of body temperature, respiratory depression, blockade of adrenocortical response. The major pathways of elimination are kidneys (urine) and the liver where it is conjugated to glucuronic acid. Opiates and their metabolites can be detected in urine as result of heroin, morphine, codeine or poppy seed intake. The CDIATM Opiate Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of opiate in urine. The CDIATM Opiate Colloidal Gold Test Cassette (Urine) yields a positive result when the opiate in urine exceeds 2000 ng/mL.