The CDIATM Phencyclidine Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of phencyclidine and its metabolites in human urine.
Phencyclidine antigen is coated on the test region of the nitrocellulose membrane of the strips, and phencyclidine antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if phencyclidine in the sample is over the detection limit, line T is blank; on the other wise, if phencyclidine in the sample is less than the detection limit, line T is red.
Phencyclidine, commonly known as PCP or “angel dust” is used primarily as recreational drug due to its hallucinogenic effects. It is generally self-administered by intravenous injection or by inhalation and concentrates fastest in fatty tissues and the brain. The effects of PCP are very much dose related. Small amounts of Phencyclidines are central nervous system stimulants that produce alertness, wakefulness, increased energy, increased heat rate, and decreased sense of pain and touch, and an overall feeling of well being. Large doses of Phencyclidine can result in death due to convulsions, heart and lung failure and coma. Large repeated doses of Phencyclidine could develop tolerances and physiological dependency and lead to its abuse. PCP can be found in urine within 4 to 6 hours after use and will remain in urine for 7 to 14 days. Phencyclidine is excreted in the urine as an unchanged drug (4% to 19%) and conjugated metabolites (25% to 30%). The CDIATM Phencyclidine Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of phencyclidine in urine. The CDIATM Phencyclidine Colloidal Gold Test Cassette (Urine) yields a positive result when the phencyclidine in urine exceeds 50/25 ng/mL.