The CDIATM Propoxyphene Colloidal Gold Test Cassette (Urine) is a lateral flow chromatographic immunoassay for the detection of propoxyphene and its metabolites in human urine.
Propoxyphene antigen is coated on the test region of the nitrocellulose membrane of the strips, and propoxyphene antibody is labeled with colloid gold. During a test, the colloid gold labeled antibody coated in the strip move forward along the membrane, and a red line will show up when the antibody gathers with the antigen in the test line; if propoxyphene in the sample is over the detection limit, line T is blank; on the other wise, if propoxyphene in the sample is less than the detection limit, line T is red.
Propoxyphene is a prescription drug for the relief of pain. Overdose of propoxyphene can have the symptoms including analgesia, stupor, respiratory depression and coma. The half-life of propoxyphene is 8 to 24 hours. Propoxyphene reaches its peak in 1 to 2 hours after oral administration. The CDIATM Propoxyphene Colloidal Gold Test Cassette (Urine) is a rapid urine-screening test that can be performed without the use of an instrument. The test utilizes a monoclonal antibody to selectively detect elevated levels of propoxyphene in urine. The CDIATM Propoxyphene Colloidal Gold Test Cassette (Urine) yields a positive result when the propoxyphene in urine exceeds 600/300 ng/mL.