CDIA™ Respiratory Syncytial Virus Test Kit - Creative Diagnostics

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Infectious Disease Tests | Respiratory Syncytial Virus |

CDIATM Respiratory syncytial virus Test Kit (DTS729)

Intended Use

The Respiratory syncytial virus Test Kit is a rapid immunochromatographic test for use in the qualitative screening of human nasopharyngeal samples for detection of the presence of respiratory syncytial virus (RSV) antigen.
  • Swab
  • Kit

Product Introduction

General Description
Respiratory syncytial virus (RSV) is the most important cause of pneumonia and bronchiolitis in infants and small children. RSV causes a range of respiratory illness, the most common being a cold with profuse rhinorrhea. Of infants infected for the first time, 25-40% develop some lower respiratory tract disease. Between 1 and 2% of infected infants require hospitalization. Because of its high infectivity and because hospital staff as well as patients are susceptible, RSV has emerged as the most frequent cause of nosocomial infections on pediatric wards. RSV belongs to the family Paramyxoviridae and the genus Pneumovirus. It is morphologically similar to other paramyxoviruses with the exception that the diameter of its helical nucleocapsid is smaller, 13 to 14 nm rather than 18 nm. RSV is an antigenically heterogeneous species, with strain differences, which are due primarily to differences in one of the two antigenically active surface components. These differences between strains are probably of little or no practical importance from a diagnostic point of view, since available reagents, including monoclonal antibodies, react equally with all clinical isolates.
Principle Of The Test
The CD RSV test strip contains a unique monoclonal antibody that is conjugated to colloidal gold particles. A polyclonal antibody is immobilized in the test area of the strip. If the nasopharyngeal sample contains RSV antigens, these will form antigen-antibody complexes with the gold particles. As these complexes migrate along the test strip to the immobilized capture antibody, a pink/purple line is formed indicating a positive test. The remaining conjugate migrates to a second antibody on the control area of the test strip forming a pink/purple band. This indicates proper performance of the test.

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