CDIATM Test kit for Y. pestis F1 antigen is a lateral flow immunoassay for qualitative detection of Y. pestis F1 antigen. It is intended to be used as a screening test and as an aid in the diagnosis of infection with Yersinia pestis.
CDIATM Test kit for Y. pestis F1 antigen is a lateral flow chromatographic immunoassay. The assay that utilized an anti-F1 polyclonal antibody to identify the bacteria was based on a double-antibody sandwich format on a nitrocellulose membrane. When an adequate volume of test specimen is dispensed into the sample well of the cassette, the specimen migrates by capillary action across the cassette. If Y. pestis F1 antigen presents in the specimen, T line and C line will appear. Absence of test line suggests a negative result. If the C line does not develop, the test result is invalid and the specimen must be retested with another device.
Yersinia pestis (Y. pestis), an infectious bacterium that is a causative agent of plague, a disease which has been shown to be one of the most feared in history and which has caused millions of deaths. The capsule-like fraction 1 (F1) antigen expressed by Y. pestis is a known specific marker for the identification of the bacteria; therefore, the detection of F1 is important for Y. pestis recognition.
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