CDIA™ Tramadol Test Cassette - Creative Diagnostics

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Drugs of Abuse Tests | Tramadol (TRA) |

CDIATM Tramadol Test Cassette (DTS248)

Intended Use

The Tramadol Rapid Test are immunochromatography based one step in vitro test. It is designed for qualitative determination of drug substances in human urine specimens. The tests are intended for use by Healthcare Professionals only.
  • Urine
  • Cassette
  • The cut-off concentrations (sensitivity level) of The Tramadol Rapid Test are determined to be: TRA 200 ng/ml.

Product Introduction

General Description
Tramadol is a quasi-narcotic analgesic used in the treatment of moderate to severe pain. It is a synthetic analog of codeine, but has a low binding affinity to the mu-opioid receptors. Large doses of tramadol can develop tolerance and physiological dependency and lead to its abuse. Tramadol is extensively metabolized after oral administration. Approximately 30% of the dose is excreted in the urine as unchanged drug, whereas 60% is excreted as metabolites. The major pathways appear to be N- and O-demethylation, glucoronidation or sulfation in the liver.
Principle Of The Test
The Tramadol Rapid Test device is based on the principle of specific immunochemical reaction between antibodies and antigen to analyze particular compound in human urine specimen. The assay relies on the competition for binding antibody. When drug is present in the urine specimen, it competes with drug conjugate for the limited amount of antibody -dye conjugate. When the amount of drug is equal or more than the cut-off, it will prevent the binding of drug conjugate to the antibody. Therefore, a positive urine specimen will not show a colored band on the test line zone, indicating a positive result, while the presence of a colored band indicates a negative result. A control line is present in the test window to work as procedural control. This colored band should always appear on the control line zone if the test device is stored in good condition and the test is performed appropriately.

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