CDIA™ Troponin I Test Cassette - Creative Diagnostics

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Cardiac Markers Tests | cTnI (troponin) |

CDIATM Troponin I Test Cassette (DTS231)

Intended Use

The Troponin I Serum/Whole Blood Rapid Test is an immunochromatography based one step in vitro test. It is designed for qualitative determination of cardiac troponin I (cTnI) in human serum, whole blood or plasma specimens as an aid in the diagnosis of myocardial infarction.
  • Serum, whole Blood
  • Cassette
  • The TnI test can detect cTnI with concentration of 0.11 ng/mL at Bayer ACS:180 or 1.5 ng/mL at Abbott AxSYM.

Product Introduction

General Description
Cardiac troponin I (cTnI) is a cardiac muscle protein with a molecular weight of 22.5 kilodaltons. Together with troponin T (TnT) and troponin C (TnC), TnI forms a troponin complex in heart to play a fundamental role in the transmission of intracellular calcium signal actin-myosin interaction. The human cTnI has an additional amino acid residues on its N -terminal that are not exist on the skeletal forms thus making cTnI a specific marker for indicating cardiac infarction. cTnI is released rapidly into blood after the onset of acute myocardial infarction (AMI). Its release pattern is similar to CK-MB (4-6 hours after the onset of AMI). However, CK-MB level returns to normal after 36-48 hours, while levels of cTnI remains elevated for up to 6-10 days. The level of cTnI is very low in normal healthy people, and not detected in patients with skeletal muscle injury. Therefore, cTnI is a specific marker for diagnosis of AMI.

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