* For research use only, not for use in diagnostic procedures.
This kit is used to qualitatively detect the existence of Cpn-IgM antibodies in serum or plasma sample, as an auxiliary clinical diagnostic reagent of (Chlamydia Pneumoniae) Cpn infection in early stage.
This kit is based on colloidal gold immunochromatography to qualitative test the Cpn-IgM antibody in serum or plasma samples. The Cpn-IgM antibodies in positive sample can combine with colloidal gold labeled mouse anti human IgM immobilized on conjugate pad to form immune complex, and move along the membrane strip by chromatography. Some of the complex is caught by recombinant Cpn Ag pre-coated on T line to form "gold labeled mouse anti human IgM-Cpn IgM Ab-Cpn Ag" and develop color. The remaining free complex will be caught by the goat anti-mouse IgG antibody coated on the C line to develop color. As for negative samples, in which have no Cpn-IgM antibodies, cannot form immune complexes and show no color on the T line, and C line appears only.
Chlamydia pneumoniae (Cpn) is a species of Chlamydophila, an obligate intracellular bacterium that infects humans and a major cause of pneumonia. It is mainly infected through the respiratory transmission and can breed in human alveolar macrophages, epithelial cells, endothelial cells, smooth muscle cells and neutrophils. Chlamydia pneumoniae is the main cause of the human atypical pneumonia, bronchitis, pharyngitis, sinusitis, otitis media, iritis, myocarditis and other diseases. 5-10% of the community acquired pneumonia, bronchitis and sinusitis was caused by chlamydia pneumoniae. In addition, epidemiology and aetiology research shows that the chlamydia pneumoniae infection is associated with cardiovascular disease.