Rapid CDIATM C. dengue kits are intended for the detection of dengue fever by detecting NS1 protein in the body.
Dengue fever is an acute mosquito-borne infection caused by the dengue viruses. This is found in tropical and sub-tropical regions around the world. Dengue fever is clinically characterised by sudden onset of high fever, severe headache, pain behind the eyes, muscle and joint pain, loss of appetite, nausea and rash. NS1 is one of 7 dengue virus non-structural proteins which are thought to be involved in viral replication. NS1 is essential for viral viability but its precise biological function is unknown. Antibodies raised in response to NS1 in viral infection can cross react with cell surface antigens on epithelial cells and platelets.