Furaltadone (FTD) is one of nitrofuran antibiotics, which can inhibit the activity of most Gram-positive and Gram-negative bacteria. FTD has been widely and illegally used for treatment of gastrointestinal disease and as growth promoters in aquatic species and livestock. FTD is unstable and can be quickly metabolized to 3-amino-5-methylmorpholino-2-oxazolidinone (AMOZ) in vivo. Normally, AMOZ is present in animal tissues as an AMOZ-protein complex for a long-term period. AMOZ also can be released from animal tissues under slightly acidic conditions. Therefore, AMOZ is often used as a target analyte for FTD residue monitoring. The residues of FTD and its metabolite AMOZ in food would be released in gastric acid conditions and absorbed by human body. It was proved that FTD and its metabolite AMOZ had the effects of mutagenesis, teratogenesis and carcinogenesis.