Insulin‐like growth factor‐binding protein 1 (iGFBP­1)

Rapid CDIA^TM iGFBP­1 kits are intended to use as a rapid method for detection of iGFBP‐1 in vaginal secretions during pregnancy.

Insulin‐like growth factor‐binding protein 1 (IBP‐1) known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene. IGF‐binding proteins (IGFBPs) is believed to be important in the regulation of fetal and neonatal growth. We previously reported that the profiles of IGFBPs in fetal cord serum (FCS) were dependent on the growth/metabolic status of the fetus. It can be detected in cervical secretions of pregnant women with preterm uterine contractions, and whether their presence predicts an increased risk of preterm delivery. Low circulating insulin‐like growth factor‐I and elevated insulin‐like growth factor binding protein‐1 levels may contribute to restricted placental and therefore fetal growth.